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2026-09-17 00:00 Papers Foundations & Methods Source language EN

Bio-MF Generates fNIRS From EEG in One Step, 857 Times Faster Than Diffusion

Summary Hybrid motor-imagery brain-computer interfaces combine EEG with functional near-infrared spectroscopy (fNIRS) to exploit complementary electrical and blood-flow signals, but wearing two headsets is cumbersome and costly, and earlier diffusion-based methods for generating one signal from the other need about a thousand iterative steps, too slow for real-time use. Researchers from the Key Laboratory of Modern Teaching Technology (Ministry of Education) at Shaanxi Normal University and Microsoft (Beijing) propose Bio-MF, which predicts fNIRS waveforms directly from EEG in a single step. On one RTX PRO 6000 GPU it produces a trial in 7 ms, 857 times faster than a 1,000-step diffusion model. Adding the synthetic fNIRS to EEG raised classification accuracy over EEG alone by 3.37 to 4.15 percentage points on one dataset, and by 2.50 to 2.98 points on a second dataset with an unseen 64-channel EEG layout. All validation was offline; the work is a preprint and has not been peer reviewed.
Why it matters Hybrid BCIs usually require two sets of sensors worn at once, and Bio-MF tries to replace the fNIRS hardware with an algorithm. Its 7 ms generation time approaches real-time requirements, but validation is offline only and the accuracy gain of 2.5 to 4.15 points is still some distance from clinical use.

BCIwiki (bciwiki.com) — Researchers at Shaanxi Normal University's Key Laboratory of Modern Teaching Technology and Microsoft in Beijing introduced, in a preprint posted to arXiv on September 17, 2026, Bio-MF, a one-step generative framework that synthesizes functional near-infrared spectroscopy (fNIRS) signals from electroencephalography (EEG) for hybrid motor-imagery brain-computer interface (BCI) decoding. The work has not been peer reviewed. Hybrid MI-BCIs combine EEG and fNIRS to exploit complementary electrophysiological and hemodynamic information, but wearing two sensor systems simultaneously is often impractical. Prior diffusion-based approaches to EEG-to-fNIRS generation require up to 1,000 iterative steps, creating latencies incompatible with real-time use.

Bio-MF performs direct signal-space prediction in a single network evaluation, integrating spatial-temporal interactive 4D encoding, cross-modal classifier-free guidance, and noise-level-gated FFT regularization to preserve task-relevant hemodynamic structure across heterogeneous sensor layouts. On Dataset 1, adding synthetic fNIRS to real EEG raised classification accuracy over EEG alone by 3.37 percentage points for deoxygenated hemoglobin (HbR) and 4.15 percentage points for oxygenated hemoglobin (HbO). On Dataset 2, gains of 2.98 and 2.50 percentage points persisted under an unseen 64-channel EEG montage. On an RTX PRO 6000 GPU, Bio-MF generates one fNIRS trial in 7.0 ms, an 857x speedup over the 1,000-step score-based conditional diffusion model baseline. The team has released its code on GitHub. All results come from offline datasets; no closed-loop online experiments have been reported.

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arxiv.org 2026-09-17
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