BCIwiki (bciwiki.com) — The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital) has registered a study with the Chinese Clinical Trial Registry to build a multimodal central-peripheral physiological signal dataset for post-stroke patients based on a non-invasive brain-computer interface, enrolling 200 stroke patients and 200 healthy controls. The registration, ChiCTR2600131692, is dated September 5, 2026. The registry lists the work as an observational, cross-sectional study with no intervention, first enrollment on October 1, 2026, and participants aged 18 to 80 in China, both sexes.
Signals span the central and peripheral nervous systems: EEG, functional near-infrared spectroscopy (fNIRS), surface electromyography (SEMG) and functional MRI (fMRI) appear among the secondary outcomes, while the primary outcome is Facial Action Units. Clinical scales include the Berg Balance Scale, Fugl-Meyer motor function, the National Institutes of Health Stroke Scale (NIHSS), the Brunnstrom stage, the Montreal Cognitive Assessment, the Fatigue Severity Scale, the Hospital Anxiety and Depression Scale (HADS) and SF-12. The registry notes that 70% to 80% of patients are unable to live independently after a stroke because of physical disability, and that recovering walking function is a crucial goal for independent living.
Inclusion requires a stroke confirmed by head CT or MRI, disease duration of 2 weeks to 2 years, Brunnstrom stage 2 to 5, a Mini-Mental State Examination (MMSE) score above 24, sitting balance grade 2 or above and a Glasgow Coma Scale (GCS) score of 15. Exclusions cover three or more prior ischemic or hemorrhagic brain injuries, severe comorbidities or complications, a history of severe motor, balance, cognitive or speech impairment, and aphasia, visual or hearing problems. Funding comes from the Anhui Provincial Health Research Project, "Multidimensional Dynamic Identification of Post-Stroke Fatigue." The record was last updated on September 7, 2026; it carries bibliographic and design fields only, with no results, device models or actual enrollment figures.