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2026-07-21 00:00 Papers Results & Follow-up Translated from EN

Case Report: 3 Stroke Patients Gain Arm Function After 24 BCI-FES Sessions

Summary Three stroke patients with hemiplegia improved on upper-limb motor scores and daily-living measures after 24 sessions of visually guided brain-computer interface training paired with functional electrical stimulation, according to a case report. The patients trained five times a week, and stimulation fired only when the system detected motor imagery-related EEG patterns; gains appeared on Brunnstrom stages, the Fugl-Meyer Assessment and the Barthel Index, most clearly in wrist and hand control. The report cautions that the findings are preliminary and require validation in larger randomized controlled trials.
Why it matters The value here is the protocol rather than the result: a concrete, clinic-deliverable dosing scheme for closed-loop BCI-FES rehabilitation, set against a three-patient uncontrolled design that shows how far the application still sits from evidence a payer or regulator would act on.

BCIwiki (bciwiki.com) — Visually guided brain-computer interface (BCI) combined with functional electrical stimulation (FES) improved upper extremity motor function and daily living activities in three hemiplegic stroke patients, particularly in wrist and hand motor control, according to a case report published on July 21, 2026, in Acupuncture & Electro-Therapeutics Research: International Journal of Integrated Medicine.

The case report, authored by Yunus Emre Doğan, describes three hemiplegic patients who underwent visually guided BCI combined with FES in addition to conventional rehabilitation. Each session consisted of a 30-minute preparation and a 30-minute treatment phase, five times a week for a total of 24 sessions. During the treatment phase, FES was triggered only when motor imagery-related EEG patterns were detected, enabling real-time patient engagement. Clinical outcomes, including Brunnstrom stages, Fugl-Meyer Assessment (FMA), and Barthel Index scores, were evaluated before and after the intervention, with improvements observed in all three cases.

The author suggests that visually guided BCI combined with FES may serve as an adjunctive rehabilitation approach for stroke patients with severe motor impairment, particularly those unable to actively participate in conventional rehabilitation. However, these preliminary findings should be interpreted cautiously, and further randomized controlled trials with larger sample sizes are required to validate clinical efficacy.

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doi.org 2026-07-21
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