BCIwiki (bciwiki.com) — According to an announcement issued by Precision Neuroscience on 2026-10-08, the company released a manuscript describing a human central nervous system atlas on bioRxiv that day. The preprint has not been peer reviewed. The company says the atlas draws on high-resolution surface electrophysiology recordings from 70 patients at 12 academic medical centers, spanning primary motor and somatosensory cortex, language and speech regions, auditory cortex, and brainstem and spinal cord structures.
The company says recordings were acquired with its Layer 7 Cortical Interface, a conformable thin-film microelectrode array that records from up to 1,024 channels at a 400-micron pitch. The manuscript's 70-patient cohort includes intraoperative and extraoperative recordings, with more than 180 hours of synchronized neural and behavioral data from 87,342 individual microelectrodes across more than 100,000 unique anatomical locations. The company also describes the atlas as comprising more than 100,000 electrode deployments. These totals do not represent simultaneous electrodes or channels in one patient.
Precision reports that the recordings resolve individual finger representations in the Rolandic cortex, with sensory polarity reversals localized to transitions as small as 0.8 mm. It also reports real-time motor decoding from upper-extremity motor cortex, spoken-word classification from ventrolateral frontal cortex, and classification of eight facial expressions from face motor cortex. Recordings additionally capture frequency-related organization in auditory-associated temporal cortex and stimulus-locked responses from the trigeminal root, dorsal columns, and thoracic spinal cord.
The company says its total number of implanted patients continued to grow after the manuscript's data collection and had surpassed 100 by the announcement. It plans to expand the atlas as patients enter its clinical studies and describes aggregation across patients and regions as a step toward a "whole-brain interface." This is the company's concept for a data resource, not a demonstration of whole-brain recording in one patient.