2026-08-25 00:00 Singapore Clinical Launch & Registration Translated from EN

Singapore's NUH Tests Lifescapes BCI for Hand Recovery After Stroke

Summary National University Hospital in Singapore has registered a clinical trial (NCT07784920) evaluating Lifescapes, an EEG-based brain-computer interface, for hand motor recovery after stroke. The 32-participant study, not yet recruiting, will compare Lifescapes therapy delivered with reduced therapist supervision against conventional rehabilitation and assess whether it is operationally feasible in the local clinical setting. Lifescapes combines motor imagery practice, biofeedback, neuromuscular electrical stimulation and robotic assistance for stroke patients with severe hand paralysis; an earlier trial in 40 patients showed improvement in motor function.

Why it matters The variable under test here is therapist time, not decoding accuracy: BCI-based stroke rehabilitation only scales if a session can run with less supervision than it needs today, and this trial measures exactly that trade-off against standard care.

BCIwiki (bciwiki.com) — National University Hospital, Singapore registered a clinical trial (NCT07784920), to evaluate Lifescapes, an EEG-based brain-computer interface, for hand motor recovery after stroke. The trial plans to recruit 32 participants and is currently not yet recruiting.Lifescapes combines motor imagery practice, biofeedback, neuromuscular electrical stimulation, and robotic assistance to aid stroke patients with severe hand paralysis. According to the trial description, a prior trial in 40 patients showed promising improvements in motor function. This study will assess whether Lifescapes therapy delivered with reduced therapist supervision can improve upper-limb motor function in stroke patients, and whether such an approach is operationally feasible in the local clinical setting.Participants will be recruited from Alexandra Hospital and National University Hospital. They must be aged 21-80, have had a stroke between 8 weeks and 5 years before enrolment, and have moderate to severe upper-limb impairment. Exclusion criteria include pregnancy, bilateral stroke, severe finger spasticity (MAS >2), implanted stimulators or pacemakers, recent seizures within 90 days, or any unstable medical conditions.Participants will complete 16 sessions of Lifescapes BCI training over 4-8 weeks (2-4 sessions per week, approximately 30 minutes each). Therapist assistance will be progressively reduced based on each participant’s ability, though a therapist remains present throughout. Each Lifescapes session is followed by a 30-minute GRASP session, a standardised self-directed arm and hand exercise programme prescribed by an occupational therapist.

Participants will attend up to 21 visits over 5-6 months. Outcomes are assessed at 6 timepoints: pre-baseline (2-4 weeks before starting), baseline, after the 8th session, after the 16th session, and at 1-month and 3-month follow-up (the latter optional). Outcome measures include the Fugl-Meyer Assessment for the upper extremity (FMA-UE), Action Research Arm Test (ARAT), grip and pinch strength, Modified Ashworth Scale (MAS), Motor Activity Log-14 (MAL-14), EQ-5D-5L quality of life measure, and optional TMS measurement of corticospinal excitability.

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clinicaltrials.gov 2026-08-25

Non-invasive BCI Singapore

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