BCIwiki (bciwiki.com) — A trial of motor imagery brain-computer interface (BCI) for motor dysfunction after stroke has been registered with the Chinese Clinical Trial Registry (ChiCTR) under number ChiCTR2600127061, with a registration date of June 23, 2026. The sponsor is The First Affiliated Hospital of Anhui University of Chinese Medicine. The interventional, parallel-group study adds BCI training to basic rehabilitation therapy in the observation arm, while the control arm receives basic rehabilitation therapy alone.
The registry lists a planned enrollment of 60 participants, 30 in each arm, with the first participant enrolled on August 10, 2022. The trial recruits in China and is listed as completed. Eligible patients are 25 to 75 years old with a first stroke confirmed by CT or MRI, a disease duration of 1 to 12 months, stable vital signs and no cognitive dysfunction, and a Modified Ashworth Scale score below grade 2 in the affected limb. Registration was not prospective.
Primary outcomes include limb motor function scores, activities of daily living, functional connectivity of relevant brain regions measured with functional near-infrared spectroscopy (fNIRS), and a lateralization index used to gauge the symmetry of that connectivity — meaning the study looks at brain-network changes alongside behavioral scores. Funding comes from the 2020 Anhui Provincial Special Fund Project for Inheritance and Development of Traditional Chinese Medicine Undertaking from Central Finance, per Document No. 5 (2020) of the Anhui Provincial Health Commission. The registry record was last updated on June 29, 2026. The registration page carries only bibliographic and design fields; it lists no results, device model or actual enrollment number.