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2026-02-01 00:00 United States Papers Foundations & Methods Translated from EN

Layer 7 Array Decodes Speech and Cursor Direction in Four Surgical Patients

阶段关键性试验适应症运动功能重建
Summary A Neurosurgical Focus paper tested Precision Neuroscience's 1,024-channel Layer 7 micro-ECoG array in four awake-craniotomy patients. Four-word speech classification reached 77.5% accuracy and four-direction cursor classification reached 78% to 84%, with no device-related adverse events reported during the procedures. The small, short intraoperative study was a feasibility test rather than a pivotal motor-restoration trial.
Why it matters Real-time speech and motor decoding from the same surface array shows platform breadth, while the intraoperative design prevents any claim about chronic therapeutic benefit.
BCIwiki (bciwiki.com) — Neurosurgical Focus published an intraoperative study of Precision Neuroscience’s Layer 7 Cortical Interface on February 1, 2026. Researchers placed the 1,024-channel micro-ECoG array, covering about 1.5 square centimeters, on the motor cortex of four patients undergoing awake craniotomy for tumors near eloquent cortex.

One patient completed an auditory-cued speech task, with four-word classification reaching 77.5% accuracy and a real-time model distinguishing speech from silence in about 20 minutes of data. Three patients completed joystick tasks, with four-direction cursor classification reaching 78% to 84% accuracy. Across six arrays, 954 to 990 channels per array were retained for analysis, and no device-related adverse events were reported during the procedures.

Layer 7 sits on the cortical surface without penetrating brain tissue. The paper demonstrates high-resolution recording and real-time decoding during a limited surgical session, but it does not evaluate chronic signal stability, infection risk or restored function. It was an intraoperative feasibility study, not a pivotal motor-restoration trial.

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Precision Neuroscience timeline

2026-09 4,096-Channel μECoG Array Maps Brain Function During Surgery With 91.3% Channel Yield 2026-08 BCI Society Workshop Tackles Outcome Measures for Pivotal Trials 2026-08 FDA Clears Precision Neuroscience's Layer 7 Cortical Interface for 30-Day Implantation 2026-07 Precision Neuroscience Hires BCI Pioneer John Donoghue as Scientific Advisor All entries →
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