BCIwiki (bciwiki.com) — KK Women's and Children's Hospital in Singapore has registered a clinical trial of brain-computer interface neurofeedback training (BCI-NFT) for children and adolescents aged 7 to 21 with acquired brain injury (ABI), with planned enrollment of 70 participants. The record was first posted on September 18, 2026, and the trial is recruiting. Its actual start date was November 1, 2025; primary completion is estimated for February 1, 2028, and overall completion for June 30, 2028.
The trial asks two questions: whether EEG-derived measures of sustained attention, relaxation and selective attention can detect and quantify cognitive impairment after acquired brain injury, and whether a structured BCI-NFT programme improves cognitive and behavioural outcomes, including attention, memory and executive function, compared with standard care alone.
The intervention group receives BCI-NFT in addition to standard cognitive rehabilitation: 12 sessions over 10 weeks, each lasting approximately 60 minutes, wearing a wireless EEG headset and interacting with neurofeedback computer games designed to respond to sustained attention, selective attention and response time. A waitlist-control group initially receives standard care alone and later crosses over to BCI-NFT, a design intended to show whether BCI-NFT produces greater improvement.
Participants complete behavioural assessments using the Behavior Assessment System for Children, Third Edition (BASC-3), including parent and/or teacher reports, and repeat them at the end of the study period. Enrollees must have had a neuropsychological assessment within the preceding 2 years and remain under review by a neuropsychologist. A separate normative cohort of children and adolescents without a history of brain injury or epilepsy attends a single session, during which EEG activity is recorded at rest and while they interact with a three-dimensional computer game, providing comparison data for the ABI participants.