This study, published in NeuroImage: Reports, improved intracortical microelectrode array implantation sites for grasp-related motor decoding by integrating anatomical, functional and vascular imaging with preoperative 3D modeling; functional imaging identified distinct grasp-related activation in the anterior intraparietal area (AIP), ventral premotor cortex (PMv) and inferior frontal gyrus (IFG).
Electrode placement was validated postoperatively using neural data collected during attempted arm and hand movements, with the arrays enabling high-fidelity decoding at a combined classification accuracy of 96%; the authors conclude this multimodal approach effectively identifies surgically feasible grasp-network implant locations in a paralyzed individual. PMID 42473457, DOI 10.1016/j.ynirp.2026.100381