Stentrode, an endovascular brain-computer interface, often picks up electrocardiogram (ECG) artifacts. Researchers at Carnegie Mellon University and colleagues found that conventional re-referencing schemes reduce ECG artifacts but also diminish beta-band activity linked to movement. They applied band-limited independent component analysis (BL-ICA) as a spatial filter to remove ECG artifacts while preserving motor features. The study appeared in Advanced Science.
The study presents an integrated ultrasonic platform that delivers high-resolution, multi-point ultrasound energy through highly aberrating barriers such as the skull and ribs, with about ±6.5% intensity uniformity across foci, using a physics-constrained metasurface design framework, and demonstrates two adaptive stimulation paradigms — attention-gated and cardiac-synchronized stimulation. A dual-channel acoustic link sustains continuous transcranial wireless power and data streaming through a single ultrasonic metasurface, remaining robust even under a 400-fold power difference. The authors frame the platform as groundwork for next-generation ultrasound-based brain-computer interfaces (uBMI) and closed-loop bioelectronic therapies.