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ALS

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July 2026

Preprint: MRI Grey Matter Loss May Predict Who Can Control an ECoG BCI in ALS

A preprint from the Utrecht-BCI Lab at the UMC Utrecht Brain Center in the Netherlands, the invasive-BCI group led by Nick Ramsey, asks why some people with ALS control an implanted brain-computer interface (BCI) better than others. It found that preservation of grey matter in the motor cortex is associated with higher-quality brain signals, suggesting an MRI-based measure could help identify who is a suitable candidate for implantation. The preprint was posted to medRxiv on June 23, 2026 (DOI 10.64898/2026.06.23.26355654).
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