BCIwiki (bciwiki.com) — A randomized clinical trial called BCI-REHAB compared an at-home brain-computer interface (BCI) therapy system with a home exercise program for upper-extremity rehabilitation in chronic stroke survivors. The trial, sponsored by Neurolutions, Inc., was conducted in the United States and first posted on ClinicalTrials.gov on July 28, 2023, with the latest update on August 12, 2026. Its status is marked as completed.
The trial used the Neurolutions IpsiHand Upper Extremity Rehabilitation System, which reads motor intentions via scalp electrodes and drives an exoskeleton hand device to facilitate repetitive hand movement training. The study aimed to evaluate the efficacy of BCI-based therapy versus standard exercise therapy and assess the potential for meaningful motor improvement in a home environment. The trial covered conditions including stroke, hemiparesis, spasticity as a sequela of stroke, and chronic stroke survivors with a plegic hand. Results have not yet been published.