2023-06-18 00:00 United States Clinical Recruitment & Enrollment Translated from EN

UT Austin Trial Tests Closed-Loop Stimulation for Cognitive Control in Older Adults

Summary The University of Texas at Austin has registered a study on ClinicalTrials.gov, NCT05907343, testing whether non-invasive stimulation can strengthen cognitive control in older adults, enrolling both people with cognitive impairment and people without it. It asks whether theta burst stimulation, a form of transcranial magnetic stimulation, can restore a range of cognitive functions, and whether delivering it in closed loop, timed to ongoing brain activity rather than on a fixed schedule, changes the result.

Why it matters Letting ongoing brain activity decide when to stimulate is the key step from fixed-schedule neuromodulation to closed-loop control. Cognitive control is a harder endpoint to quantify than motor symptoms, which makes the trial design itself worth watching.

BCIwiki (bciwiki.com) — The University of Texas at Austin has registered a clinical study on ClinicalTrials.gov, trial identifier NCT05907343, investigating whether noninvasive stimulation can enhance cognitive control in older adults.

The study enrolls older adults both with and without cognitive impairment. According to the registration, the questions it aims to answer include whether various cognitive functions can be restored by delivering theta burst stimulation, a form of transcranial magnetic stimulation, and what difference closed-loop delivery makes.

Closed-loop stimulation times delivery according to ongoing brain activity rather than following a fixed schedule.

Compiled by BCIwiki from public sources

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clinicaltrials.gov 2023-06-18

University of Texas at Austin Transcranial Magnetic Stimulation Closed-loop Systems Non-invasive BCI United States

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