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2019-03-22 00:00 United States Clinical Results & Follow-up Translated from EN

Vanderbilt Uses Post-Op CT Scans to Guide Cochlear Implant Programming

Summary Vanderbilt University Medical Center has developed a method that uses post-operative CT scans and image processing to determine the physical relationship between cochlear implant electrodes and the neural interface, allowing sub-optimally positioned electrodes to be switched off for a customized map. Cochlear implants are surgically implanted devices that restore hearing by electrically stimulating the auditory nerve, and their programming has traditionally ignored where the electrodes actually sit. The trial tested whether this individualized image-guided programming improves hearing and speech outcomes in pediatric recipients, with hearing measures collected at baseline, 12 months and 24 months; it has been completed, but results have not been posted.
Why it matters Cochlear implants are in routine clinical use and are still programmed without reference to where the electrodes ended up; if image-guided fitting proves out in children, the same anatomy-aware argument applies to every implanted electrode array that came after them.

BCIwiki (bciwiki.com) — Vanderbilt University Medical Center has developed a method using post-operative CT scans and image processing to determine the physical relationship between cochlear implant electrodes and the neural interface, allowing customized mapping by deactivating sub-optimally positioned electrodes. The approach, termed "Image-guided Cochlear Implant Programming" (IGCIP), was registered on ClinicalTrials.gov on March 22, 2019, under identifier NCT03886168.

Cochlear implants are surgically implanted devices that restore hearing by electrically stimulating the auditory nerve. Programming (mapping) involves turning on each electrode and adjusting stimulus levels to a comfortable and beneficial level. The current standard-of-care mapping does not consider the physical location of electrodes relative to the neural interface. Vanderbilt's method uses post-operative CT and image processing to specify this spatial relationship, enabling deactivation of poorly positioned electrodes.

The trial evaluated whether IGCIP significantly improves outcomes in pediatric cochlear implant patients, with hearing measures collected at baseline, 12 months, and 24 months. According to ClinicalTrials.gov, the study status is completed, but results have not been posted on the registry.

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