BCIwiki (bciwiki.com) — Surgeons in Michigan implanted Paradromics' Connexus brain-computer interface into the brain of a patient with motor neuron disease in June 2026, according to Neurotech Pub. The female participant had lost most of her ability to speak. Connexus reads individual neurons through 421 microelectrodes placed 1.5 millimeters into the motor cortex; signals run to a transceiver in her chest, which beams them to a receiver, and AI turns them into words on a screen.
Paradromics, an Austin-based neurotechnology company, received FDA approval last fall (2025) to begin the clinical trial. CEO Matt Angle said the surgery went well and the patient recovered. A machine learning algorithm is learning to read her brain and produce speech, and she is relearning how to use a voice and the device. Angle noted that this is what the clinical phase looks like.
Angle also addressed misconceptions about brain-computer interfaces, saying the field is not niche and will turn untreatable biology problems into solvable technology problems over the next decade. He predicted a revolution in mental health within ten years, using BCIs to read out signatures of mental illness. He also advocated for ongoing support payment models to prevent patients from being abandoned with non-functional devices if companies run out of money.