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March 2019

Vanderbilt Uses Post-Op CT Scans to Guide Cochlear Implant Programming

Vanderbilt University Medical Center has developed a method that uses post-operative CT scans and image processing to determine the physical relationship between cochlear implant electrodes and the neural interface, allowing sub-optimally positioned electrodes to be switched off for a customized map. Cochlear implants are surgically implanted devices that restore hearing by electrically stimulating the auditory nerve, and their programming has traditionally ignored where the electrodes actually sit. The trial tested whether this individualized image-guided programming improves hearing and speech outcomes in pediatric recipients, with hearing measures collected at baseline, 12 months and 24 months; it has been completed, but results have not been posted.
Why it matters Cochlear implants are in routine clinical use and are still programmed without reference to where the electrodes ended up; if image-guided fitting proves out in children, the same anatomy-aware argument applies to every implanted electrode array that came after them.
May 2017

Johns Hopkins begins early feasibility trial of bidirectional cortical neuroprosthesis

Johns Hopkins University is conducting an early feasibility study to evaluate the safety and efficacy of the Bidirectional Cortical Neuroprosthetic System (BiCNS). The system comprises NeuroPort Microelectrode Array Systems, NeuroPort Electrodes (Sputtered Iridium Oxide Film), Patient Pedestals, the NeuroPort BioPotential Signal Processing System, and the CereStim C96 Programmable Stimulator. The trial enrolls patients with tetraplegia and quadriplegia and is currently recruiting.
Why it matters This clinical trial record details an early feasibility study of the BCI device BiCNS, with verifiable specifics on device components, conditions, and trial status, making it a valuable clinical update.

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